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Löffler's serum : ウィキペディア英語版 | Löffler's medium Löffler's medium is a special substance used to grow diphtheria bacilli to confirm the diagnosis. == History == In 1887, Friedrich Loeffler devised a culture medium containing horse serum, meat infusion, and dextrose for use in the cultivation of corynebacteria and for differentiating them from other organisms.〔Loeffler, F. 1887. Darauf theilte Herr Loeffler en einem Zweiten vortrag die ergebnisse seiner weiteren unter suchungen uber die Diphtherie- Bacillen mit. Zentralbl. Bakteriol. Parasitenkd. 2:105-112.〕 Perry and Petran suggested modification of the original formulation.〔Perry, C.A., and E.I. Petran. 1939. Routine laboratory examinations for C. diphtheriae. J. Lab. Clin. Med. 25:71-78.〕 Buck, in 1949, described a modified Loeffler's medium for cultivating ''Corynebacterium diphtheriae''.〔Buck, T.C. 1949. A modified Loeffler's medium for cultivating ''Corynebacterium diphtheriae''. J. Lab. Clin. Med. 34:582-583.〕
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